Warning regarding Fumaric Acid for Psoriasis treatment.

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Warning regarding Fumaric Acid for Psoriasis treatment.

Postby Nick Balgowan » Mon Sep 18, 2006 6:02 pm

A user here was promoting "Fumaric Acid" which is essentially a food additive, and there is NO clinical evidence to JUSTIFY if for psoriais treatment. Note the referrence below from Wikipedia says "Sometimes used to treat psoriasis" but I think this should read NO LONGER USED TO TREAT PSORIASIS and an UNRECOGNISED TREAMTMENT FOR PSORIASIS. I have reported this abuse of our system to this person's internet service provider. I am being forced to remove several accounts like this every day and I really wonder why these people do not have better things to do with their time

Fumaric acid
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Fumaric acid

Common name fumaric acid
Systematic name (E)-butenedioic acid
Other names trans-1,2-ethylenedicarboxylic acid

Fumaric acid (IUPAC systematic name: 2-butenedioic acid), also called allomaleic acid, boletic acid or lichenic acid, is a colorless crystalline flammable carboxylic acid based on butene and molecular formula C4H4O4. Irritating maleic anhydride fumes are produced by its combustion. Having a fruitlike taste, it is found in fumitory (Fumaria officinalis), bolete mushrooms (specifically Boletus fomentarius var. pseudo-igniarius), lichen, and Iceland moss.

Fumaric acid is an acid used in the manufacture of polyester resins and polyhydric alcohols, as a mordant for dyes, or as a flavoring. It is a common component of food additives and dietary supplements, and is sometimes used as a substitute for tartaric acid in beverages or baking powder.

Related to malic acid, fumaric acid is used by cells to produce energy from food. Human skin naturally produces fumaric acid when exposed to sunlight.

Fumaric acid esters are sometimes used to treat psoriasis, as it has been suggested that the condition is caused by an impairment of fumaric acid production in the skin. A starting dose is 60-105mg daily, which may be gradually increased to as much as 1,290mg per day. Side effects include kidney or gastrointestinal disorders, as well as skin flushing; these are mainly caused by excess intake. Decreased white blood cell counts have been reported with prolonged use.

Fumaric acid is a food acidulant used since 1946 because it is non-toxic. It is generally used in beverages and baking powders for which requirements are placed on purity, such as Welch's Grape Drink. It is generally used as a substitute for tartaric acid and occasionally in place of citric acid, at a rate of 1.36 g of citric acid to every 0.91 grams of fumaric acid for the same taste
Nick Balgowan.
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